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Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Names 

 

Description


Patient Groups

Bloggers

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
ANCA-associated vasculitis
AAV
Granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis
Microscopic polyangiitis
Churg-Strauss syndrome

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of diseases characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, stomach, intestine, and lung. Skin lesions, such as purpura and urticaria, result when blood from small vessels leaks under the skin. AAV occurs when neutrophils attack small and medium vessels of the body. The underlying reason for this remains unclear.

Vasculitis Foundation

We have not found any current bloggers for this disease. If you are one, or know someone who is, please contact us.

Prevalence

US Cases: 15,000 - 60,000

Source: American College of Rheumatology

Typical Age of onset

Varies depending on type of vasculitis; estimates range from 15 to 70 years old. (No data referenced.)

 

Symptoms

These symptoms vary depending on the type of vasculitis:

  • Fever

  • Headache

  • Fatigue

  • Weight loss

  • General aches and pains

  • Night sweats

  • Rash

  • Nerve problems, such as numbness or weakness

Sources: Mayo Clinic, American Academy of Family Physicians, NIH-US National Library of Medicine