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Autoimmune neutropenia

Names

 

Description

Autoimmune neutropenia (AIN)
Autoimmune neutropenia of infancy
Primary autoimmune neutropenia
 

Autoimmune Neutropenia is caused by the production of IgG antibodies that target and destroy the body’s own neutrophils, which leads to a lowered white blood cell count and leaves patients with weakened immune systems susceptible to bacterial and other infections.

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Prevalence

3,000 persons in the US

Source: Arthritis Research & Therapy (journal article)

Typical Age of onset

Autoimmune Neutropenia often presents at birth, but goes into remission by age 3 in 95% of cases

Symptoms

  • Weak immune system (recurring infections)

  • Mouth ulcers and inflammation of the gums

  • Sore throat

  • Chest infections

  • Diarrhea

  • High fevers and chills

  • Exhaustion/Lethargy