Bullous pemphigoid is a rare, autoimmune, chronic skin disorder characterized by blistering. This disorder occurs most frequently in elderly people. Generalized blistering occurs in and under the upper layers of the skin and usually subsides spontaneously within several months or years. In some rare cases of Bullous pemphigoid, complications such as pneumonia may develop.
Typical Age of onset
Average age at onset of 65 years.
- Large blisters that don't easily rupture when touched
- Eczema or hive-like rash rather than blisters
- Blisters on lower abdomen, groin, upper thighs & arms
- Itchy in affected areas
- Blisters or sores in mouth
- Blisters on eyes
- vegetating plaques on areas of the skin, such as the armpit, neck, groin, and breasts (very uncommon)
1. In childhood-onset bullous pemphigoid associated with vaccination, the bullous lesions predominantly affect the palms, soles, and face
2. In infants, blisters tend to occur frequently on the palms, soles, and face, affecting the genital areas rarely