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Felty syndrome

Evidence: Antibody

Names

Felty Syndrome
FS
Super rheumatoid disease

Description

Felty syndrome is a rare, potentially serious disorder which is characterized by the presence of three symptoms : rheumatoid arthritis, splenomegaly (enlarged spleen) and neutropenia (a decreased white cell count) which can lead to repeated infections.  It also associated with seropositive (rheumatoid factor (RF) – positive rheumatoid arthritis.

Patient Groups

None available

Bloggers

None available

Prevalence

US Cases: 32,000 [Calgüneri 2006]. FS affects about 1-3% of all people diagnosed with rheumatoid arthritis (RA), which occurs in about 1% of the general population.

Typical Age of onset

FS is most common during the fifth through seventh decades of life and is usually associated with having 10 years of RA preceding it. It is 3 times more common in women than men.

Symptoms

  • Painful, stiff and swollen joints most commonly in the joints of the hands, feet, and arms.

  • Fever

  • Fatigue

  • Weight loss

  • Anemia

  • Thrombocytopenia

  • Vasculitis