Guillain-Barre syndrome


Guillain–Barré syndrome


Guillain–Barré syndrome (GBS) is when the immune system attacks and damages part of the peripheral nervous system, leading to muscle weakness or tingling sensations in the legs, arms, or upper body. Severity varies, with some patients experiencing heart and breathing issues that require emergency medical attention. The cause of GBS is unknown but GBS can occur after a viral or bacterial infection.

Typical Age of onset

Onset can occur at any age but most common in adults ages 30-50


  • Tingling and weakness that starts in the feet and legs, the arms, or the face.
  • Tingling or weakness that has spread. If it began in the legs, it usually spreads to the upper body.
  • Trouble making usual eye or facial movements, such as those involved in speaking, chewing, or swallowing.
  • Difficulty breathing in general, or feeling short of breath while lying flat.
  • Difficulty walking or climbing stairs.
  • Difficulty with bladder control, or having abnormal bowel function.
  • Severe pain. May be aching or cramping. May be worse at night time.
  • Rapid heart rate
  • Abnormally low or high blood pressure

Source: Mayo Clinic