Pediatric Acute-onset Neuropsychiatric Syndrome


Pediatric Acute-onset Neuropsychiatric Syndrome
Pediatric Autoimmune Neuropsychiatric Disorder associated with Streptococcus


Both PANDAS and PANS are diseases of children and adolescents marked by obsessive compulsive disorder (OCD) and tic disorder symptoms that begins after a bacterial infection.  If the condition starts after a streptococcus infection, it is called PANDAS. PANS is associated with infection triggered autoimmune responses that attack normal body tissues by mistaking them for similar infectious agents.


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Typical Age of onset

Childhood - Age 3
Adult - 35


Easy or excessive bruising (purpura)
Rash - pinpoint-sized reddish-purple spots (petechiae) usually on the lower legs
Bleeding from the gums or noseBlood in urine or stools
Unusually heavy menstrual flow

Sources:  Mayo Clinic, Healthline