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Systemic Lupus Erythematosus

Names

 

Description

 

 

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Systemic Lupus Erythematosus
SLE
Lupus

SLE, the most common type of lupus, is a chronic inflammatory disease that occurs when the body's immune system attacks its own tissues and organs. Inflammation caused by lupus can affect many different body systems — including joints, skin, kidneys, blood cells, brain, heart and lungs.

Molly's Fund
Lupus Research Alliance

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Prevalence

The Lupus Foundation of America estimates prevalence to be at least 1.5 million cases. This includes milder forms of the disease

Notes:
1.Higher prevelance among women
2. Incidence in the US:  Between 1970s to 2000s have ranged from approximately 1 to 10 per 100,000 population

Typical Age of onset

Onset of SLE is usually after puberty, typically in the 20s and 30s, with 20% of all cases diagnosed during the first 2 decades of life.

Symptoms

  • Fatigue and fever
  • Joint pain, stiffness and swelling
  • Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose
  • Skin lesions that appear or worsen with sun exposure (photosensitivity)
  • Fingers and toes that turn white or blue when exposed to cold or during stressful periods (Raynaud's phenomenon)
  • Shortness of breath
  • Chest pain
  • Dry eyes

Source: Medscape