Systemic lupus erythematosus






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Systemic lupus erythematosus

SLE, the most common type of lupus, is a chronic inflammatory disease that occurs when the body's immune system attacks its own tissues and organs. Inflammation caused by lupus can affect many different body systems — including joints, skin, kidneys, blood cells, brain, heart and lungs.

Molly's Fund
Lupus Research Alliance



The Lupus Foundation of America estimates prevalence to be at least 1.5 million cases. This includes milder forms of the disease
Source: Medscape

1.Higher prevelance among women
2. Incidence in the US:  Between 1970s to 2000s have ranged from approximately 1 to 10 per 100,000 population

Typical Age of onset

Onset of SLE is usually after puberty, typically in the 20s and 30s, with 20% of all cases diagnosed during the first 2 decades of life.


  • Fatigue and fever
  • Joint pain, stiffness and swelling
  • Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose
  • Skin lesions that appear or worsen with sun exposure (photosensitivity)
  • Fingers and toes that turn white or blue when exposed to cold or during stressful periods (Raynaud's phenomenon)
  • Shortness of breath
  • Chest pain
  • Dry eyes

Source: Medscape