Anti-Glomerular Basement Membrane nephritis



Anti-Glomerular Basement Membrane Disease
Anti-GBM Disease
Goodpasture’s Disease

Anti-GBM Disease is a rare but serious autoimmune disease that affects the lungs and kidneys. It occurs when the body’s immune system mistakenly produces antibodies against collagen in the lungs and kidney. Collagen is a protein that helps form connective tissue


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Prevalence of Anti-GBM Disease in the US has never been studied.

Typical Age of onset

Anti-GBM Disease affects people who are between ages 20 and 30 and older than age 60.


  • Fatigue

  • Nausea

  • Vomiting

  • Weakness

  • Trouble breathing

  • Pale skin

  • Coughing up blood (hemoptysis)

  • Burning feeling when urinating

  • Blood in the urine (hematuria)

  • Protein in the urine (proteinuria)