Anti-neutrophil cytoplasmic antibody-associated vasculitis
Evidence: T Cell
Names
Description
Patient Groups
Bloggers
Anti-neutrophil cytoplasmic antibody-associated vasculitis
ANCA-associated vasculitis
Granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis
Microscopic polyangiitis
Churg-Strauss syndrome
Wegener’s Granulomatosis
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of diseases characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, stomach, intestine, and lung. Skin lesions, such as purpura and urticaria, result when blood from small vessels leaks under the skin. AAV occurs when neutrophils attack small and medium vessels of the body. The underlying reason for this remains unclear.
We have not found any current bloggers for this disease. If you are one, or know someone who is, please contact us.
Prevalence
US Cases: 15,000 - 60,000 [Berti 2017]
Typical Age of onset
Varies depending on type of vasculitis; estimates range from 15 to 70 years old. (No data referenced.)
Symptoms
These symptoms vary depending on the type of vasculitis:
Fever
Headache
Fatigue
Weight loss
General aches and pains
Night sweats
Rash
Numbness
Weakness
Source: Mayo Clinic
