Acute rheumatic fever
An inflammatory disease that may develop as a complication of inadequately treated strep throat or scarlet fever that can cause permanent damage to the heart including damaged heart valves and heart failure.
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Typical Age of onset
- Painful and tender joints — most often in the knees, ankles, elbows and wrists
- Pain in one joint that migrates to another joint
- Red, hot or swollen joints
- Small, painless bumps (nodules) beneath the skin
- Chest pain
- Heart murmur
- Flat or slightly raised, painless rash with a ragged edge (erythema marginatum)
- Jerky, uncontrollable body movements (Sydenham chorea, or St. Vitus' dance) — most often in the hands, feet and face
- Outbursts of unusual behavior, such as crying or inappropriate laughing, that accompanies Sydenham chorea