Sjögren’s syndrome




Sjögren's syndrome
Sicca syndrome (generally refers to the non-autoimmune form of this condition)
Keratoconjunctivitis sicca (a symptomatic diagnosis not specific to autoimmune disease)

Sjogren's syndrome is a disorder of your immune system identified by its two most common symptoms — dry eyes and a dry mouth.

Sjogren's syndrome often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased production of tears and saliva.


Sjrogren's prevalence is estimated from 1.75 million to as many as 9 million cases in the United States

Source: The epidemiology of Sjögren’s syndrome

Typical Age of onset



  • Dry mouth
  • Dry eyes
  • Gritty or burning sensation in the eyes
  • Joint pain
  • Joint swelling
  • Joint stiffness
  • Swollen salivary glands
  • Rashes
  • Dry skin
  • Vaginal dryness
  • Persistent dry cough
  • Prolonged fatigue
  • Sources:  Mayo Clinic, Healthline