Primary biliary cholangitis
Evidence: Antibody
Names
Primary biliary cholangitis (formerly primary biliary cirrhosis)
PCB
Description
Primary biliary cholangitis is chronic disease in which the bile ducts of the liver are slowly destroyed due to inflammation with progressive scarring.
Patient Groups
Bloggers
N/A
Prevalence
US Cases: 94,000 [Lu 2017]
Typical Age of onset
Ages 30-60
Symptoms
Early Symptoms
● Fatigue
● Itchy skin
● Dry eyes and mouth
Late Symptoms
● Pain in upper right abdomen
● Bone, muscle, or joint pain
● Swollen feet and ankles
● Buildup of fluid in abdomen due to liver failure
● Fatty deposits on skin around eyes, eyelids, or in the creases of the palms, soles, elbows or knees
● Jaundice
● Hyperpigmentation
● Osteoporosis
● High cholesterol
● Diarrhea
● Underactive thyroid
● Weight loss
