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Autoimmune lymphoproliferative syndrome

Evidence: T Cell

Names

Autoimmune lymphoproliferative syndrome
ALPS
Canale-Smith syndrome

Description

Autoimmune lymphoproliferative syndrome is a genetic disease that causes overproduction of lymphocytes, leading to enlargement of lymph nodes (lymphadenopathy), the liver (hepatomegaly), and the spleen (splenomegaly).

Patient Groups

None

Bloggers

None

Prevalence

US Cases: Under 200 estimated (less than 500 worldwide) [Shah 2014]

Typical Age of onset

No specific age

Symptoms

  • Enlargement of lymph nodes

  • Enlargement of spleen

  • Enlargement of liver

Resources

References

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