Gestational Pemphigoid
Evidence: Antibody
Names
Pemphigoid gestationis
PG
Herpes gestationis
Description
This disease is a rare autoimmune disease that affects the skin of pregnant women. Patients experience a rash accompanied by blisters and extreme itching on the abdomen or limbs, which may spread elsewhere. Onset is sudden, often occurring during the second and third trimester. It is common for the condition to go into remission at the end of pregnancy and then to relapse during birth. Most patients experience full recovery within 6 months of giving birth, though some have reported that symptoms may last for years. The condition is uncomfortable but does not put the patient at risk. Treatments are available to manage symptoms as needed.
Patient Groups
International Pemphigus & Pemphigoid Foundation
Bloggers
None
Prevalence
US Incidence: 100 - 3,000 per year. Estimates range from 1 per 2,000 to 1 per 60,000 pregnancies. There are about 6 million pregnancies in the US per year (CDC - 2009). [Fong 2020]
Typical Age of onset
Most common between weeks 28 and 32 of pregnancy [Fong 2020]
Symptoms
Itchy, hive-like rash
Red bumps on abdomen or trunk
Large blisters or raised patches on affected area
