Prevalence

US Cases: 66,000 - 70,000 [Wang 2018 and Lim 2014], based on 29% of patients with SLE developing lupus nephritis. SLE prevalence as reported by Georgia and Michigan registries: 72.1-74.4 per 100,000 people (Lim 2014).

Note from Lim: Black women had an incidence rate nearly 3 times higher than that for white women with a significantly higher rate in the 30 to 59 years age group … . The age-adjusted prevalence rate for women was nearly 9 times higher (127.6 vs. 14.7) than that for men. Black women had very high rates (196.2). A striking difference was seen in the proportion with end-stage renal disease in prevalent cases, with a sevenfold greater involvement among blacks.

Typical Age of onset

 At least 3 years after SLE symptoms begin to appear (SLE may occur at any age but most common in women of child-bearing age)

Source:
Musa et al (2020)
Vaillant et al (2020)

Symptoms

• Weight gain

• High blood pressure

• Swelling in your legs, ankles, arms, and hands that worsens throughout the day

• Blood in your urine

• Headache and dizziness

• Nausea and vomiting

• Foamy urine

• Rash or ulcers of the nose or mouth

Resources

Link to Clinical Trials

Link to Scientific Publications

References

American College of Rheumatology
Medline
Mayo Clinic
Medscape
Musa et al (2020)
Vaillant et al (2020)
WebMD

Profile by Salma Fleifil