Restless leg syndrome


Restless leg syndrome
Willis-Ekbom Disease


A condition that causes an unpleasant or uncomfortable sensation in the legs and an irresistible urge to move them.


US cases: ~12 million
Source: Sleep Medicine

Typical Age of onset

Early onset begins before 45 and late onset begins after 45


  • Sensations that begin after rest. The sensation typically begins after you've been lying down or sitting for an extended time, such as in a car, airplane or movie theater.
  • Relief with movement. The sensation of RLS/WED lessens with movement, such as stretching, jiggling your legs, pacing or walking.
  • Worsening of symptoms in the evening. Symptoms occur mainly at night.
  • Nighttime leg twitching. RLS/WED may be associated with another, more common condition called periodic limb movement of sleep, which causes your legs to twitch and kick, possibly throughout the night, while you sleep.