Intermediate uveitis
Evidence: T Cell
Names
Intermediate uveitis
IU
Chronic cyclitis
Peripheral uveitis
Vitritis
Cyclochorioretinitis
Peripheral uveoretinitis
Pars planitis
Description
Intermediate uveitis is a disorder that causes inflammation in the vitreous humour, the gel that fills the eye. In this condition, cells from the blood may penetrate the eye’s interior and be found suspended in the vitreous humour. Normally, both eyes are affected. Patients with the pars planitis subtype of intermediate uveitis also have additional inflammation in the pars plana (the layer of the eye between the iris and the vitreous humour). This occurs when cells from the vitreous humour leak into the pars plana. This subtype is more common in children, while non-pars planitis intermediate uveitis is more common in adults. The non-pars planitis subtype is especially common in those with systemic conditions, such as sarcoidosis and multiple sclerosis, or in those who have certain infections. Some cases without infection may be caused by autoimmune activity. Patients of both pars planitis and non-pars planitis subtypes often experience floaters and blurry vision. Without medical attention, vision loss and blindness may occur in severe cases; however, treatments are available to prevent this.
Patient Groups
Prevalence
US Cases: 4,000 – 6,000 [Ness 2017]. 1.4 – 2 per 100,000 persons.
Typical Age of onset
Non-pars planitis subtype: most common in adults between 30 and 49
Pars planitis subtype: most common in children 6-10 years of age
[Özdak and Tugal-Tutkun 2019]
Symptoms
Blurred Vision
Floaters (small specks that float in field of vision)
Visual Loss
Eye Pain
Redness of the eye
Light sensitivity
