Linear IgA disease
Evidence: Antibody
Names
Linear IgA disease
Linear IgA bullous disease
Chronic bullous dermatosis of childhood
Linear IgA dermatosis
Description
Linear IgA disease causes blisters to form deep in the skin. It can affect the skin and mucus membranes such as the mouth and genitals. Its name comes from the image produced during a skin biopsy in which a line of IgA antibodies can be found just below the outer layer of skin (the epidermis).
Patient Groups
None
Bloggers
None
Prevalence
US Cases: 150 - 700 [Fortuna 2012].
Typical Age of onset
It affects young children usually before the age of 5 and adults usually over the age of 40.
Symptoms
Blisters or lesions in the skin of the trunk, scalp, face, and limbs, or mucus membranes (mouth, anus, or genitals) in a clustered arrangement
Lesions are often itchy and may burn
In children, the perineum is often involved
